9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T74824 | TGR5 agonist 1 | ||
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1]. | |||
T40302 | FXR/TGR5 agonist 1 | ||
FXR/TGR5 agonist 1 acts as an agonist on both FXR and TGR5 receptors and is utilized for treating fatty liver disease. | |||
T1824 | TGR5 Receptor Agonist | GPCR19 | |
TGR5 is a potent TGR5(GPCR19) agonist. | |||
T8818 | TC-G 1005 | GPCR19 | |
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available. | |||
T74825 | TGR5 agonist 2 | ||
TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1]. | |||
T81000 | TGR5 Receptor Agonist 4 | ||
TGR5 Receptor Agonist 4, a selective agonist for the Bile Acid Receptor (TGR5), exhibits potent activity with an EC50 of 2 nM for human TGR5 (hTGR5) and 3 nM for mouse TGR5 (mTGR5). It is notably involved in mediating hy... | |||
T79425 | TGR5 agonist 4 | ||
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1]. | |||
T63554 | TGR5 Receptor Agonist 3 | ||
TGR5 Receptor Agonist 3 is a G protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist soft drug compound that decreases gallbladder filling, exhibits good gallbladder safety, and is able to act on hTGR5 (EC50: 16.4 ... | |||
T79424 | TGR5 agonist 3 | ||
Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1]. |